36 research outputs found

    Do UK universities communicate their brands effectively through their websites?

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    This paper attempts to explore the effectiveness of UK universities’ websites. The area of branding in higher education has received increasing academic investigation, but little work has researched how universities demonstrate their brand promises through their websites. The quest to differentiate through branding can be challenging in the university context, however. It is argued that those institutions that have a strong distinctive image will be in a better position to face a changing future. Employing a multistage methodology, the web pages of twenty UK universities were investigated by using a combination of content and multivariable analysis. Results indicated ‘traditional values’ such as teaching and research were often well communicated in terms of online brand but ‘emotional values’ like social responsibility and the universities’ environments were less consistently communicated, despite their increased topicality. It is therefore suggested that emotional values may offer a basis for possible future online differentiation

    Transcranial Direct Current Stimulation (tDCS): A Beginner's Guide for Design and Implementation

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    Transcranial direct current stimulation (tDCS) is a popular brain stimulation method that is used to modulate cortical excitability, producing facilitatory or inhibitory effects upon a variety of behaviors. There is, however, a current lack of consensus between studies, with many results suggesting that polarity-specific effects are difficult to obtain. This article explores some of these differences and highlights the experimental parameters that may underlie their occurrence. We provide a general, practical snapshot of tDCS methodology, including what it is used for, how to use it, and considerations for designing an effective and safe experiment. Our aim is to equip researchers who are new to tDCS with the essential knowledge so that they can make informed and well-rounded decisions when designing and running successful experiments. By summarizing the varied approaches, stimulation parameters, and outcomes, this article should help inform future tDCS research in a variety of fields

    Identifying Low Pharmaceutical Calculation Performers Using an Algebra-Based Pretest

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    Objective: To determine if a pretest assessing algebra-based problem solving skills could aid in identifying those who may underperform in calculations course assessments and if this provides additional value beyond pre-admission and demographic characteristics. Methods: Student pharmacists were screened for algebraic problem solving skills using an 18-item pretest taken the semester prior to a course containing pharmaceutical calculations content. These scores were compared to later performance on pharmaceutical calculations assessments. Linear regression models were computed to determine the relationship between pretest scores and pharmaceutical calculations performance, after controlling for pre-admission factors and demographic characteristics. Results: The median pretest score was 15 out of 18 possible points, with scores ranging from 5 to 18 correct. After controlling for age, gender, ACT scores, and high-school GPA, scores on the algebra-based, word-problem pretest were associated with performance on pharmaceutical calculation assessments. Conclusion: This research demonstrates the ability of a pretest, aimed at identifying deficiencies in algebraic problem solving skills, to identify those at risk of failing to obtain mastery of pharmaceutical calculations, even after controlling for demographics, prior grades, and prior standardized test scores. Identifying these students is a first step towards implementing tailored interventions to improve students\u27 algebra-based word problem skills in order to prevent deficiencies in pharmaceutical calculations mastery before class even begins

    Low frequency of HLA-DRB1*11 in hepatitis C virus induced end stage liver disease

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    Hepatitis C virus (HCV) infection becomes chronic in more than 70% of patients, leading to end stage liver disease in about 20-30% of these patients. Apart from the virus itself, host factors that modulate the immune response are likely to be involved in determining the outcome of HCV infection. Studies on the association of human leucocyte antigens (HLAs) and HCV infection have shown inconsistent results. Selection of patient subgroups may be crucial. However, any association relevant to HCV disease progression will become evident, especially in those patients with end stage liver disease. Therefore, we analysed the phenotype frequencies of HLA antigens in two groups of 69 and 39 patients with HCV induced liver cirrhosis who had received a transplant or were awaiting liver transplantation. The first group was typed serologically and compared with 331 blood and liver donors. The second group, prospectively HLA typed by a polymerase chain reaction-sequence specific oligonucleotide (PCR-SSO) procedure for HLA-DRB and DQB alleles, was compared with another 170 PCR-SSO typed and randomly selected blood donors. Decreased frequencies for HLA-DR5 and HLA-DQ3 were found in one group of patients with HCV induced liver cirrhosis compared with the control groups. In the second analysis comparing 39 patients with end stage liver cirrhosis with blood donors, we confirmed the significant decrease in HLA-DRB1*11 and HLA-DQB1*03, which corresponded to serological HLA-DR5 and HLA-DQ3 antigens, respectively. Our results show that the presence of HLA-DRB1*11 and HLA-DQB1*03 alleles is associated with a reduced risk for the development of HCV induced end stage liver disease.


Keywords: hepatitis C; HLA; liver cirrhosis; immunogenetics; hepatocellular carcinoma; genotyp
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